JUUL ME ONCE…Another study found that e-cigarettes cause DNA damage in the lungs which is comparable to regular cigarettes
- Researchers at McGill University, Canada, exposed mice to 60 puffs per day
- They found that the rodents showed signs of lung damage within one month
- Vaping has become an epidemic in America’s youth amid attractive advertisements
Another study on e-cigarettes indicates that vaping – vaping for just one month – results in DNA damage comparable to smoking tobacco.
Researchers at McGill University in Montreal, Canada, exposed mice to the equivalent of 60 puffs of the mango-flavored Juul per day for four weeks.
Rodents suffered from cellular and molecular changes associated with the formation of cancer in conventional cigarette smokers.
America is currently in the grip of an epidemic of child vaping that has been blamed on kid-friendly flavors and attractive storefront displays.
Another study suggests that vaping – vaping for just one month – leads to ‘widespread changes’ in the lungs and increases inflammation levels (file photo)
Official figures show that at least 2.6 million American children between the ages of 11 and 18 use e-cigarettes, and the number is rising.
In the latest study, scientists exposed mice to air from a nicotine-containing Juul device.
One-third of the rats were blasted with 60 Joule puffs per day, in three 20-minute sessions with a three-hour interval between each session.
The researchers said this was to mimic low use of vaping devices.
In a November survey, one in ten teens admitted to using vapes within five minutes of waking up — a sign of addiction — while a quarter said they vaped daily.
The rest of the mice were exposed to the e-liquid used in vapes, or just air in the lab.
The e-liquid — used to create the vapor — contains propylene glycol, a petroleum by-product, and vegetable glycerin from vegetable oil.
The study focused on Juul, but studies have shown that other brands also have a harmful effect on the lungs.
Many vape devices contain e-liquids that contain hundreds of chemicals that can be harmful to the lungs. They also contain nicotine, which can lead to e-cigarette addiction.
Four weeks later, the scientists killed the mice and examined their lungs for signs of the effects of the Joule machines.
The results showed that the mice exposed to e-cigarette vapors had higher levels of white blood cells in their lungs, which indicates higher levels of inflammation.
The tests also detected changes in hundreds of genes in macrophages – another type of white blood cell involved in the immune response to infection or damage.
They said the alterations they observed indicated an increased risk of vaping-related lung injury (EVALI).
Symptoms of the condition include shortness of breath, chest pain, coughing, and hemoptysis — or coughing up blood. In severe cases, it can lead to death.
Since 2019, thousands of cases have been reported across the United States, with the condition most strongly associated with e-cigarettes.
The researchers concluded: ‘Thus, e-cigarettes are not inert and can cause significant cellular and molecular changes in the lungs.
Dr Carolyn Pagel, an expert in experimental medicine at McGill University, said: ‘The health consequences of vaping are unknown.
Our results show that inhaling vapor from a popular brand of e-cigarette causes widespread changes within the lungs.
“The data that further demonstrates that these products are not inert and may lead to lung damage if used long-term.”
She added, “We have shown that low-level aerosols of chronic exposure have local immunomodulatory effects, and radically alter protein and RNA expression at important lung sites.”
DailyMail.com has contacted Juul for comment.
Dual use of e-cigarettes and traditional cigarettes at the same time exacerbates the risks
Combustible e-cigarettes and traditional cigarettes on their own can cause a host of inflammatory and heart problems
– When used simultaneously, the health effects can be worse
Long-term use of either caused damage to blood vessels, although each caused some adverse effects that the other did not, suggesting that dual use of the products compounded the damage.
Blood from e-cig users caused blood vessel cells to permeate more than blood from tobacco smokers and non-users, which increases the risk of cell damage and heart disease.
Blood from tobacco smokers had higher levels of some common biomarkers of cardiovascular risk
The study’s lead author said that using both products together “can increase their health risks compared to using them individually.”
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